Retatrutide Raw Materials Powder CAS 2381089-83-2 Fast Shipping Worldwide

Retatrutide is a triple agonist peptide of glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide -1 receptor (GLP-1R). Retatrutide binds to human GCGR, GIPR and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively. Retatrutide can be used in the study of obesity.

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Retatrutide  is a unique single-peptide triple agonist, and its molecule is composed of 39 amino acids. In this structure, three key non-coding amino acid residues play a vital role. Aib2, namely α-aminoisobutyric acid, is like a loyal guardian. It can effectively improve the stability of retalukast, resist the degradation of dipeptidyl peptidase-4(DPP4), ensure that the drug can maintain its activity in the body, and lay a foundation for the subsequent treatment.

Aib20, like a fine designer, helps to optimize GIP activity, pharmacokinetics and exploitability, and makes the drug function in the body more accurate and efficient. And αMeL13(α- methyl -L- leucine), as a clever regulator, optimizes the activities of glucagon (GCG) and GIP, so that the drug can better exert the triple excitation effect.

In addition, the skeleton is combined with albumin through C20 fatty diacid linker located at the 17th lysine residue. This design is like installing a "battery life enhancer" for the drug, which not only prolongs the half-life of the drug, but also endows it with the required pharmacological properties, thus supporting the triple excitatory activity of retalukast.

In addition, as a peptide drug in the research and development stage, the study of its impurities is the core link of drug quality control, which is directly related to the safety and efficacy. Omizzur also supplies all kinds of peptides and impurities of retatrutide for scientific research.

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Powder:  -20°C  3 years  /   4°C  2 years

In solvent:  -80°C  6 months /  -20°C  1 month

Shipping: Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

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Omizzur specializes in custom peptide synthesis, providing professional peptide synthesis services to pharmaceutical R&D companies worldwide. Our product offerings include pharmaceutical-grade peptides, cosmetic peptides, peptide impurity synthesis, and amino acid derivatives. For more peptide product information, please contact Omizzur custom peptide synthesis.

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