TB-500 API Raw Material CAS  ‌885340-08-9 | Thymosin β4 fragment 

TB-500 is a synthetic molecule of the active region of thymosin β 4. TB-500 can promote endothelial cell differentiation, angiogenesis in dermal tissue, migration of keratinocytes, collagen deposition, and reduce inflammation.

TB-500, as a carefully designed synthetic molecule, it accurately simulates the key active region of thymosin β 4, a bioactive peptide. Thymosin β 4 plays multiple roles in the body, particularly exhibiting significant effects in cell repair, regeneration, and inflammation regulation.

TB-500 not only inherits many advantages of its parent molecule, but also demonstrates more outstanding performance in specific application fields.

TB-500 API Synthesis with High Purity

TB-500 (Acetate Thymosin β 4 Fragment) is a bioactive peptide composed of a fragment of thymosin β 4 protein, which is obtained through esterification treatment. It has the property of promoting wound repair and tissue regeneration.

The preparation of acetate thymosin beta 4 fragment is usually achieved through chemical synthesis methods. The thymosin β 4 protein molecule was subjected to acetic acid esterification reaction, and the final acetate thymosin β 4 fragment was obtained through purification, structural identification, and other steps.

Acetate thymosin beta 4 fragment (TB-500) is widely used in research and clinical practice. Its main applications include wound repair, tissue regeneration, treatment of chronic ulcers, and promotion of muscle and bone injury rehabilitation.

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TB-500 Application Fields and Research Areas

1.Muscle/Tendon/Ligament Repair: Accelerate muscle fiber regeneration, collagen deposition, and tendon remodeling, reduce post exercise micro injuries and chronic strain injuries, muscle tears, tendinitis, and postoperative soft tissue recovery

2. Wound healing: accelerate epithelization, reduce scar, promote burn/ulcer/surgical incision healing skin wounds, corneal injuries, diabetes foot ulcers (experiment)

3. Cardiovascular repair: protects myocardial cells, promotes angiogenesis and myocardial remodeling after myocardial infarction, improves cardiac function, myocardial infarction, ischemia-reperfusion injury (animal experiments)

4. Neural repair: Activate oligodendrocytes, promote myelin regeneration, alleviate neuroinflammation, spinal cord injury, traumatic brain injury, and peripheral neuropathy (experiment)

5. Bone and Joint Repair: Promote osteoblast proliferation and callus formation, improve joint cartilage repair for fractures, non union, and osteoarthritis (experimental)

6. Eye repair: promote corneal epithelial healing, reduce intraocular inflammation, protect retinal cells from corneal damage, dry eye syndrome, and retinal ischemia (experiment)

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