MOTS-c
| Name | MOTS-c | |
| Type | Peptide API | |
| CAS | 1627580-64-6 | |
| Purity % (HPLC) | > 99.0% (HPLC) | |
| Pack size | Price ( USD ) | Inventory |
| 1 gram | US$ 500.0 | In stock |
| 50 gram | Please inquire | In stock |
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General Description
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a novel mitochondrial derived peptide composed of 16 amino acids, expressed in various tissues and plasma, acting on cells, participating in the regulation of body metabolism, and exerting protective effects. In the heart, mitochondria are important activating organelles involved in various mechanisms such as oxidative stress, autophagy, and apoptosis.
Research has shown that MOTS-c has important cardioprotective effects and can participate in the pathophysiological processes of cardiovascular disease through various mechanisms. Therefore, it is speculated that MOTS-c is highly likely to be associated with the occurrence and development of atrial fibrillation, and it may become a novel biomarker for predicting the occurrence and development of atrial fibrillation.
Clinical Application and Prospect of MOTS-c
Based on the important findings of this study, MOTS-c has broad application prospects in multiple medical fields:
1.In terms of cardiovascular disease, MOTS-c may become an adjuvant drug for myocardial infarction reperfusion therapy, reducing reperfusion injury and improving patient prognosis
2.In the field of neuroprotection, MOTS-C may provide a new option for stroke treatment by protecting the integrity of the blood-brain barrier
3.In terms of muscle diseases, the membrane repair function of MOTS-c may have therapeutic effects on diseases such as muscular dystrophy. Research data shows that MOTS-c can significantly reduce exercise-induced muscle injury, which also brings new intervention ideas to the field of sports medicine.
Future research needs to further address several key issues, such as the optimal dosing regimen for MOTS-c, long-term safety assessment, and specific distribution in different tissues. In addition, exploring the synergistic effect of MOTS-c with other repair factors and developing a combination therapy strategy based on MOTS-c is also a research direction worth paying attention to
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MOTS-c Research
MOTS-c (human) is a type of mitochondrial derived peptide (MDP). The main physiological function is to promote the biosynthesis of endogenous AMP analog AICAR, thereby promoting AMP activated protein kinase (AMPK), while also enhancing the induction of glucose uptake demand in cells and improving insulin sensitivity. As a pharmaceutical ingredient, it can be considered a potential weight loss peptide material and has good anti-aging effects.
Photos of Omizzur MOTS-c API peptide raw materials products

Product Data Sheet
| Name | MOTS-c (API) |
| CAS | 1627580-64-6 |
| Appearance | White lyophilized powder |
| Source | Synthetic peptide |
| Molecular formula | C101H152N28O22S2 |
| Molecular weight | 2174.59 |
| Sequence | H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH |
| Purity(HPLC) | >99.0% |
| Packing specifications | 1g/5g/10g/custom-made |
| Shipping | FedEx/DHL/EMS/By air |
| Delivery time | 5~10 days normally |
| Analysis data | HPLC,MS,COA. Accept certification |
| Storage | Store at 2-8 C or-20 C in the dark. |
Shipping & Storage

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