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Acute coronary syndrome (ACS) is a serious threat to human health. The use of antiplatelet drugs is one of the key steps in the treatment. Platelet glycoprotein Ⅱ B / Ⅲ a receptor is the final common pathway of platelet thrombosis. Blocking this receptor can effectively inhibit platelet aggregation stimulated by various inducers. Its antagonist has become a new, powerful and more reasonable drug for the treatment of ischemic heart disease.
ASC patients have a rapid onset, high mortality and high disability rate. During clinical first aid, the treatment time window should be grasped. Drugs are required to play a role quickly and inhibit platelet function. Under the condition of good tolerance of clinical patients, the higher the platelet aggregation inhibition rate, the better the curative effect, and better prevent thrombosis and myocardial infarction for further treatment. Eptifibatide is a peptide antiplatelet aggregator. By inhibiting platelet aggregation to prevent the formation of thrombosis, it has the advantages of strong antiplatelet effect, rapid onset, and less adverse reactions. Eptifibatide showed a rapid anti platelet aggregation effect, and the platelet aggregation was significantly inhibited after 1 min of administration. It is mainly used for acute coronary syndrome (ACS), preventing myocardial feeding artery occlusion, heart attack, sudden death caused by coronary intervention, etc.
The liquid phase peptide synthesis method is more suitable for large-scale synthesis of Eptifibatide . By converting lysine to high arginine and oxidizing DTT to cyclopeptide, the production cost can be reduced and the purity and yield of crude products can be improved. Omizzur also provides various Eptifibatide impurities for research.
Product Data Sheet
|Type||Peptide antiplatelet aggregators|
|Purity (HPLC)||98.0% min|
|Source||Custom peptide synthesis|
Shipping & Storage
It is valid for at least one year if stored at -20 ℃ or lower. Since each freezing and thawing of polypeptide will cause partial inactivation, after the storage solution with corresponding concentration is prepared for the first time (please prepare the storage solution according to the information in the column of reconstitution in the product introduction), it must be frozen at -20 ℃ or lower after sub packaging to avoid repeated freezing and thawing.
Shipping: By air or FedEx Express, delivery time: 5-10 days
Matters Needing Attention:
This product is freeze-dried powder. Since a small amount of polypeptide is deposited in the tube during the freeze-drying process, forming a very thin or invisible polypeptide layer, before opening the tube cover, we recommend centrifuging about 8000-12000g in a centrifuge for 10-30 seconds to make the polypeptide attached to the tube cover or tube wall gather at the bottom of the tube.
This product is only used for scientific research by professionals, and shall not be used for clinical diagnosis or treatment, food or drugs, or stored in ordinary houses.
For your safety and health, please wear lab clothes and disposable gloves.
1. For all batches of products, we will keep samples after one year of validity. When customers raise objections, we can make a quick response.
2. For the products purchased by customers, an original of our inspection report will be attached with the goods, including batch number, date, etc.
3. If you have any problems in use, please feel free to contact us and we will help you solve them as soon as possible.
1. After you confirm the purchase, please inform our sales staff of your detailed requirements, including product name, quantity, packaging requirements, etc., as well as your receiving address, company name and contact information; Then our sales staff will make an order for you.
2. Omizzur is a professional peptide manufacturer, there will be a huge discounts for bulk purchase. Distributors are welcomed.
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