Atosiban

Atosiban CAS 90779-69-4 | Omizzur
* For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Name

Atosiban

TypeOxytocin analogs
CAS

90779-69-4

Purity % (HPLC)> 98.0% (HPLC)
Pack size

Price ( USD )

Inventory
200mg$  /
In stock
1 gPlease inquire
In stock
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General Description

Atosiban  CAS 90779-69-4

Atosiban is a cyclic nonapeptide, an oxytocin analog, a competitive antagonist of oxytocin receptors in the uterus, decidua, and fetal membranes. To achieve the purpose of protecting the fetus, it is clinically used for the treatment of premature birth.


Atosiban is a combined receptor antagonist of oxytocin and vasopressin V1A. Its chemical structure is similar to that of the two, and it has a high affinity for receptors and competes for binding to oxytocin and vasopressin V1A receptors. , thereby blocking the action pathway of oxytocin and vasopressin and reducing uterine contractions.


In the Omizzur solid-phase synthesis method, RinkAmide and AMResin are coupled one by one to obtain a linear peptide resin, and then the solid-phase oxidation resin, cleavage and purification are used to obtain atosiban acetate.


Product Data Sheet

Name

Atosiban 

CAS

90779-69-4

Type

Oxytocin analogs

Sequences

deamino-Cys(1)-D-Tyr(Et)-Ile-Thr-Asn-Cys(1)-Pro-Orn-Gly-NH2

Purity

98% min

Molecular formula

C43H67N11O12S2

Molecular weight

994.2

Source

custom peptide synthesis

Application

Premature drug research


Shipping & Storage

It is valid for at least one year if stored at -20 ℃ or lower. Since each freezing and thawing of polypeptide will cause partial inactivation, after the storage solution with corresponding concentration is prepared for the first time (please prepare the storage solution according to the information in the column of reconstitution in the product introduction), it must be frozen at -20 ℃ or lower after sub packaging to avoid repeated freezing and thawing.

Shipping: By air or FedEx Express, delivery time: 5-10 days


Matters Needing Attention:

This product is freeze-dried powder. Since a small amount of polypeptide is deposited in the tube during the freeze-drying process, forming a very thin or invisible polypeptide layer, before opening the tube cover, we recommend centrifuging about 8000-12000g in a centrifuge for 10-30 seconds to make the polypeptide attached to the tube cover or tube wall gather at the bottom of the tube.

This product is only used for scientific research by professionals, and shall not be used for clinical diagnosis or treatment, food or drugs, or stored in ordinary houses.

For your safety and health, please wear lab clothes and disposable gloves.



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