Boc-C16-NHS ester
| Name | Boc-C16-NHS ester | |
| Type | Activated ester | |
| CAS | 843666-34-2 | |
| Purity % (HPLC) | > 99.0% (HPLC) | |
| Pack size | Price ( USD ) | Inventory |
| 1 gram | US$ 100.0 | In stock |
| 1 KG | Make Inquiry | In stock |
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General Description
Boc-C16-NHS ester, CAS No. 843666-34-2, is a long-chain alkyl-type protective group activation reagent that integrates three functional modules: the Boc protecting group, a hydrophobic hexadecyl long chain, and the reactive NHS ester. Specifically designed for hydrophobic modification, directional conjugation, and controlled deprotection of amino-containing biomolecules, it serves as a key intermediate in lipidosome modification, protein hydrophobicity modification, amphiphilic molecule synthesis, and targeted carrier construction.
Product type: NHS active ester, long-chain alkyl modification reagent, amino coupling reagent.
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| Common Peptide Fragments | |||
| AEEA | 134978-97-5 | Fmoc-AEEA | 166108-71-0 |
| Boc-AEEA | 108466-89-3 | AEEA-AEEA | 1143516-05-5 |
| Boc-AEEA-AEEA | 1069067-08-8 | Fmoc-AEEA-AEEA | 560088-89-3 |
| 14-(tert-Butoxy)-14-oxotetradecanoic acid | 234082-00-9 | 18-(tert-Butoxy)-18-oxooctadecanoic acid | 843666-40-0 |
| Semaglutide Intermediates | |||
| Fmoc-L-Lys[Oct-(otBu)-Glu-(otBu)-AEEA-AEEA]-OH | 1662688-20-1 | Ste-Glu-AEEA-AEEA-OSU | 1169630-40-3 |
| tBuO-C18-Glu(AEEA-AEEA-OSu)-OtBu | 1118767-15-9 | tBuo-C18-OSu | 843666-34-2 |
| Boc-His(Trt)-Aib-OH | 2061897-68-3 | Fmoc-His-Aib-OH | 1446013-07-5 |
| Tirzepatide Intermediates | |||
| Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA-AEEA]-OH | 2915356-76-0 | C20-OtBu-Glu(OtBu)-AEEA-AEEA-OH | 1188328-37-1 |
| tBuO-C20-Glu-OtBu | 1119061-70-9 | Boc-Tyr(tBu)-Aib-OH | 2639221-78-4 |
| Fmoc-Ile-Aib-OH | 2171139-20-9 | Fmoc-Ala-Pro-OH | 186023-44-9 |
| Retatrutide Intermediates | |||
| Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA]-OH | 2612237-97-3 | tBuo-C20-Glu(AEEA)-OtBu | 2645421-68-5 |
| tBuo-C20-OSu | 1119061-69-6 | tBuO-C20-Glu-OtBu | 1119061-70-9 |
| Fmoc-Thr(tBu)-Phe-OH | 1962160-86-6 | Fmoc-Pro-Pro-OH | 129223-22-9 |
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Application Fields
Boc-C16-NHS ester is widely used in organic synthesis, functional material development, and biomolecule modification in scientific research fields. Can be used for long-chain alkylation modification of peptides, polymers, dendritic molecules, nanomaterials, and surface active materials, introducing stable hydrophobic structures.
In addition, Boc-C16-NHS ester can also be used for solid-phase synthesis, molecular coupling, surface functionalization, microsphere modification, and other scientific experiments that require the introduction of long-chain fatty alkyl structures, providing stable and efficient chemical tools for the design and construction of functional molecules.
Product Data Sheet
| Name | Boc-C16-NHS ester |
| Alias | Octadecanedioic acid |
| CAS | 843666-34-2 |
| Type | Amino coupling reagent |
| Molecular formula | C₂₆H₄₅NO₆ |
| Molecular weight | 467.64 |
| Purity (HPLC) | >99.0% |
| Melting point | 51°C |
| Density | 1.15±0.1 g/cm3 |
| Appearance | White to light yellow solid/powder |
| Analysis report | HPLC, MS, COA |
| Storage | store at -20±5°C |
| Shipping | By Fedex / UPS/ by Air |
| Sales Market | North America, Europe, Middle East, Africa, Asia |
Shipping & Storage
Storage conditions
It is recommended to store the product in a sealed, dry, and dark environment at low temperatures to avoid moisture and prolonged exposure to air. NHS active esters are prone to hydrolysis with water, and it is recommended to store and use them under anhydrous conditions.
The prepared solution should be used as soon as possible and avoid repeated freeze-thaw cycles to maintain the coupling activity and chemical stability of the product.
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