What is Selank Peptide | Benefits and Dosage

What is Anxiety Disorder?

Anxiety disorder is a type of mental illness that endangers people's healthy lives. With the increasing economic development and social competition, there is a significant increase in anxiety patients. According to statistics, the incidence rate rate of urban population in developing countries is about 1%~2%, while that in developed countries is nearly 10%, and it is still growing.

Clinical anti anxiety drugs such as diazepam, buspirone, and fluoxetine have varying degrees of side effects. Although the symptoms of each type of anxiety disorder are different, the affected individuals often have obvious symptoms of autonomic nervous system dysfunction, such as palpitations, shortness of breath, excessive sweating, dizziness, nausea, and abdominal pain, which cause varying degrees of distress to patients' daily lives. There is an urgent need to develop new anti anxiety drugs with high efficacy and few toxic side effects.

Currently, major pharmaceutical companies around the world are conducting research on anti anxiety drugs, mainly focusing on GABA receptors, peripheral benzodiazepine receptor (PBR), 5HT receptors, ccKB (choleyetokinin B) receptors, cFR (Conicotmpin releasing Factor Receiver), histamine receptors, NMDA receptors, and cholinergic ion channels, among which Selank Peptide is a popular peptide research project.

What is Selank Peptide?

Selank belongs to a class of small molecules called synthetic peptides. Selank was made by combining the sequence of a peptide called tuftsin with another sequence that improves its molecular stability. Tuftsin is a peptide closely related to immune function. It occurs naturally and makes up one part of the natural antibody IgG.

It is a small peptide compared to most naturally occurring proteins. Selank was developed at the Institute of Molecular Genetics in cooperation with the V.V. Zakusov Research Institute of Pharmacology (Russian Academy of Medical Sciences), at present, this peptide can be rapidly synthesized in Omizzur laboratory.

Selank Peptide Benefits

While most prescription drugs cause many unwanted side effects, studies have shown this peptide to have no negative side effects or risk of addiction. Both Tuftsin and Selank have shown the ability to reduce anxiety and increase serotonin levels in animal models.

Additionally, selank peptide may:

1. Improve anxiety 

2. Improve learning

3. Enhance memory 

4. Help with brain damage recovery: Increases BDNF (Brain-derived neurotrophic factor), an important brain-growth compound

5. Help stabilize enkephalins in the blood: These counteract the stress response

6. Help with alcohol withdrawal

7. Help prevent weight gain and reduce cholesterol

Selank Peptide Analysis Data

Selank Peptide Animal Experiments

Selank is a synthetic derivative of the tetrapeptide tuftsin that contains a proline-glycine-proline sequence at the C-terminus and has anxiolytic and anti-inflammatory activities. It increases the amplitude and discharge rate of inhibitory postsynaptic currents of neurons in the rat hippocampal CA1 region when used at a concentration of 1 μM. It decreases the level of affective responses and the number of erroneous escape attempts in rats in an acute stress situation, increases orientational-investigative responses of rats in an unfamiliar situation, and reduces the time mice spend immobile in the forced swim test. 

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