SS-31 Raw Material | CAS 736992-21-5 | Elamipretide‌

SS-31 is a small molecule peptide composed of four amino acids. (D-Arg-dimethylTyr-Lys-Phe-NH ₂) has a special cationic and aromatic structure, which can actively cross the cell membrane and accurately locate the inner mitochondrial membrane. Its original design intention is to protect mitochondrial structure, enhance energy metabolism, and combat oxidative stress and cell apoptosis.

SS-31 helps improve mitochondrial function and enhances overall energy production through ATP synthesis. Research shows that it can reduce inflammatory cytokines that lead to oxidative stress and inflammatory diseases (such as Alzheimer's disease, Parkinson's disease, heart disease, diabetes, kidney disease, etc.).

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SS-31 has shown significant effects in multiple disease models

 1. Cardiovascular health

Animal and human clinical studies have shown that SS-31 can reduce myocardial ischemia-reperfusion injury and improve myocardial mitochondrial energy metabolism, demonstrating potential therapeutic value in chronic heart failure.

2. Muscle function improvement

In both elderly and mouse models, SS-31 significantly improved exercise endurance, enhanced mitochondrial respiratory capacity, and reversed age-related muscle decline.

3. Degenerative eye diseases

Research has found that SS-31 can improve age-related macular degeneration (AMD) and optic neuropathy, and may even be used to treat mitochondrial diseases such as Leber hereditary optic neuropathy (LHON).

4. Renal protective effect

In acute kidney injury and chronic kidney disease models, SS-31 exhibits the ability to inhibit tubular apoptosis and alleviate oxidative stress.

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SS-31 Safety Statement

For scientific research purposes only: not suitable for clinical, diagnostic, or therapeutic use on the human body; Non dietary supplements/drugs

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