Palmitol Pentapeptide-4 | Matrixyl Acetate | CAS 214047-00-4

The reduction of collagen in the dermis of the skin is considered to be the main reason for the formation of wrinkles in human aging. Therefore, if the skin can be promoted to synthesize more collagen, it will effectively reverse aging and reduce wrinkles.

Palmitoyl pentapeptide-4 is the earliest and most widely used multi-peptide in the peptide series, and many world-renowned brands are using it as an important ingredient in anti-wrinkle formulas. It can penetrate the dermis to increase collagen, reverse the process of skin aging by rebuilding from the inside out; stimulate the proliferation of collagen, elastic fibers and hyaluronic acid, improve the skin's water content and water retention, increase skin thickness and reduce fine lines.

Palmitoyl pentapeptide-4 Mechanism of Action

Palmitoyl pentapeptide 4 is a signal peptide of Matrikine (polypeptide-like fragment acting as a messenger in the natural tissue repair process), which acts on dermal fibroblasts to promote macromolecular substances such as type I, III, and IV collagen, fiber Synthesis of connexin and glycosaminoglycans, repair and reconstruction of extracellular matrix and epidermal-dermal junction (DEJ), solve wrinkle problem and improve skin appearance from deep in the skin. At the same time, palmitoyl pentapeptide-4 can also promote the expression of wound repair genes, which is beneficial to the recovery of skin tissue.

Palmitoyl Pentapeptide-4 is a small molecule that readily penetrates the skin and is structurally similar to the precursor of type I collagen. Pentapeptides are thought to communicate with cells and program them to perform specific actions, including repair work.

Palmitoyl Pentapeptide-4 is a pentapeptide synthetic chain protein produced by linking five amino acid peptides. According to research, this chain reacts in the dermis of the skin, stimulating collagen and elastin fibroblasts to form fibronectin (FN) and glycosaminoglycans (GAG). Palmitoyl Pentapeptide-4 has anti-wrinkle effects. Several independent research organizations have conducted and published studies demonstrating the anti-wrinkle efficacy of this peptide (in vitro and in vivo)

Efficacy of Palmitoyl Pentapeptide-4

Relevant experimental studies have shown that palmitoyl pentapeptide-4 can effectively prevent and reduce wrinkles, making the skin younger, smoother and more elastic. The anti-wrinkle effect and activity of palmitoyl pentapeptide-4 are far superior to conventional vitamin A and vitamin C, and it has no side effects. This makes palmitoyl pentapeptide-4 more advantages in anti-wrinkle skin care: it can be used as facial care and body care anti-aging; eye repair; face, neck and hand care products.

Independent in vitro studies (unlike most palmitoyl pentapeptide-4 studies done by Matrixyl's founders, P&G) showed a 212% increase in Type I collagen synthesis and a 100% to 327% increase in Type IV collagen, Hyaluronic acid increased by 267%. Of the 19 types of collagen found in the human body, type I collagen predominates; therefore, increasing collagen I production has a very dramatic effect on rebuilding the skin.

A six-month in vivo study showed a 17% reduction in average wrinkle depth, a 68% reduction in the surface area containing deep wrinkles, a 51% reduction in the surface area containing moderate wrinkles, and a 16% reduction in skin roughness.

Palmitol Pentapeptide-4 Product Features

Palmitoyl Pentapeptide-4 can effectively promote the proliferation of collagen, hyaluronic acid and elastic fibers in the skin, increase the water content of the skin, increase the thickness of the skin, eliminate static lines, and enhance the firmness and gloss of the skin.

Appearance: white powder

Solubility: fat soluble

Molecular weight: 802.05

Moisture: 8%

Peptide content: 80%

Purity: 95%

Acetic acid: 15%

Application: Eye and face anti-wrinkle and aging cream, lotion, essence products

Recommended dosage: 0.003%-0.02%

Packing: 10g, 50g, 100g/plastic bottle

Storage: Store in a cool, dry and dark place, store in the refrigerator at 2-8 degrees

Shelf life: 2 years under the above storage conditions

1. Peptides in the form of lyophilized powder provided can be stably transported under normal temperature through sealed packaging.Peptides requiring long-term preservation shall be stored in a sealed container containing desiccant in the form of lyophilized powder and stored at a temperature below - 20 centigrade, which can avoid peptide degradation, bacterial degradation and oxidation, and the formation of secondary structure of peptide.

2. Shipping: Deliver to worldwide by Fedex / DHL  （Free shipping for orders over a certain amount）

3. Provide with the goods: quality analysis report (COA,MS,HPLC) ,Other corresponding analysis reports.

1. Cosmetic peptide products include but are not limited to the above varieties,contact us by customer services: [email protected]

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4. Discount : Omizzur has regular discount on wholesale quantity.Periodic and regular centralized purchasing will save a lot of transportation costs.