Fmoc-D-Phe(2-Me)-OH
| Name | Fmoc-D-Phe(2-Me)-OH | |
| Type | Unnatural amino acids | |
| CAS | 352351-63-4 | |
| Purity % (HPLC) | > 99.0% (HPLC) | |
| Pack size | Price ( USD ) | Inventory |
| 5g | US$ 120.0 | In stock |
| 100g | Please inquire | In stock |
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General Description
Fmoc-D-Phe(2-Me)-OH is an unnatural amino acid derivative of phenylalanine, which can be used in the synthesis of peptides and is often used in scientific research.
Unnatural amino acids (ncAAs) play a wide and important role in the application of peptides, which are mainly reflected in structural optimization, functional enhancement, improvement of pharmaceutical properties and construction of new materials. Their core applications can be summarized as follows:
Improve the pharmaceutical properties of peptide
Enhance stability: resist protease/peptidase degradation and prolong half-life.
Improve pharmacokinetics: improve water solubility, reduce immunogenicity and optimize biological distribution.
Typical application: GLP-1 receptor agonists, such as smegrupeptide and liraglutide, all contain unnatural amino acid modifications to prolong the in vivo action time.
A series of unnatural amino acids have been used for protein modification in bacteria, yeast and mammalian cells with high accuracy and efficiency. Most of them are derivatives of 20 natural amino acids.
The unnatural amino acid derivatives reported today include phenylalanine derivatives, tyrosine derivatives, glutamine derivatives, alanine derivatives, cysteine derivatives, serine derivatives, lysine derivativesand so on.
Omizzur Biotech now supplies a large number of amino acid derivatives for peptide synthesis.
Product Data Sheet
| Name | Fmoc-D-Phe(2-Me)-OH |
| CAS | 352351-63-4 |
| Synonyms | Fmoc-D-Phe(2-Me)-OH , Fmoc-d-2-methylphenylalanine, Fmoc-D-2-CH3-Phe |
| Molecular formula | C25H23NO4 |
| Molecular weight | 401.45 |
| Appearance | Powder |
| Melting point | 110-116℃ |
| Boiling point | 631.1±55.0 °C(Predicted) |
| Density | 1+-.0.06 g/cm3(Predicted) |
| pka | 3.81±0.11(Predicted) |
| optical activity | 47.4°(C=0.01g/mL, DMF, 20°C, 589nm) |
| Analysis report | MS, HPLC, COA |
| Storage | Sealed in dry, 2-8C |
Shipping & Storage
Global delivery, shipping by air/ FedEx/ DHL/EMS.
−20°C (−15°C to −25°C) for long time.
Ordering Guide:
Order Fmoc-D-Phe(2-Me)-OH now:
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About Omizzur Ltd
Omizzur specializes in amino acid derivatives and peptide synthesis, providing professional peptide synthesis services to pharmaceutical R&D companies worldwide. Our product offerings include pharmaceutical-grade peptides, cosmetic peptides, peptide impurity synthesis, and unnatural acid derivatives. For more product information, please contact Omizzur custom peptide synthesis.
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