Fmoc-Cit-OH | 133174-15-9 | Unnatural amino acids

Fmoc-Cit-OH (Fmoc-L-citrulline) is an amino acid derivative containing the Fmoc protecting group, which can be used to construct degradable ADC linkers based on the Val-Cit unit.

Main Applications

1.Solid-phase peptide synthesis: As a functionalized amino acid monomer with protecting group, the Fmoc protecting group can be removed gently with organic amines such as piperidine.

2.ADC linker synthesis: A degradable antibody-drug conjugate linker used for constructing the Val-Cit unit.

3.Research Probe: Capable of preparing targeted detection reagents for studying autoimmunity disease target peptides, antimicrobial activity peptides, and related research. ‌‌

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Unnatural amino acids refer to those that do not exist in the polypeptide chains of living organisms. They contain diverse side chain groups and play significant roles in various fields such as medicine, bioengineering, agriculture, and cosmetics.

In the field of medicine, non-natural amino acids can directly serve as drugs in their monomeric form to exert biological activity, or be incorporated into macromolecular drugs to enhance efficacy or reduce side effects, offering new perspectives for disease diagnosis and the development of novel pharmaceuticals;

In the field of bioengineering, non-natural amino acids are widely used to analyze and modify the structure and function of proteins, enhancing their activity and application scenarios. They also play a significant role in the research and development of novel biomaterials.

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Fmoc-Cit-OH CAS 133174-15-9 | Omizzur Peptide

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