Neuropeptide Y (NPY) CAS:213779-13-6 high purity best price for life science research!

Neuropeptide Y (NPY) is a hormone that widely exists in the central and peripheral and maintains homeostasis. In the central nervous system, NPY has the function of anti anxiety and anti epilepsy, and it can inhibit reproduction, muscle excitation and sympathetic excitation, resulting in the decrease of blood pressure, heart rate and metabolism. It can also promote appetite, and therefore becomes the target of diet drugs. However, peripheral NPY has a positive stimulatory effect, which enhances stress response together with glucocorticoid and catecholamine. NPY can induce vascular contraction, vascular smooth muscle proliferation, increase blood lipid, glucose tolerance and release adipocytokines.

Neuropeptide Y (NPY) is a 36 amino acid neuropeptide, which is widely distributed in the central and peripheral nervous system. It is one of the most abundant peptides in mammalian nervous system. In 2014, many studies found that NPY is closely related to epilepsy

Detection of neuropeptide Y:

RIA is the most commonly used method with high sensitivity (pmol level), but there are many interferences. It is suggested that the blood samples should be properly purified before analysis, and the samples should be concentrated at the same time, which can greatly reduce the interference and make the results more reliable.

If the sample is stored at minus 80 ° C, there is no problem without adding enzyme inhibitor. If it is added, it also depends on whether it interferes with RIA. If it is added, add liquid and then dry to reduce the liquid. The whole RIA operation should be carried out in an ice box.

Biotinyl-Neuropeptide Y

CAS:213779-13-6

Sequence:Biotin-YPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY-NH2

Total sequence:Biotin-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2

Source: synthetic

Purity: 95%, 98%

Salt system: TFA, HAC, HCl or others

Storage condition:− 20 ° C

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