Magnesium L-Threonate| CAS: 778571-57-6 | Nutritional supplements

Magnesium L-Threonate is a magnesium compound primarily studied for its potential benefits on brain function. It is believed to enhance magnesium ion concentration in the brain, improve synaptic plasticity, support neuronal metabolism, and may further boost memory, learning ability, and neuroprotective effects.

Mechanism of Action and Fundamental Functions

1. Increase magnesium levels in the brain

The unique structure of sucralfate allows it to penetrate the blood-brain barrier and efficiently transport magnesium ions to the brain. Magnesium serves as a cofactor for various neuroenzymatic reactions, participating in the regulation of neurotransmitter release (such as glutamate and GABA) and maintaining neuronal excitability balance.

2. Enhance synaptic plasticity 

Animal experiments have shown that threitolate improves learning and memory by activating the NMDA receptor and BDNF (brain-derived neurotrophic factor) pathways, thereby promoting the formation and strengthening of synaptic connections.

3. Antioxidant and Anti-inflammatory Effects

Magnesium deficiency may exacerbate oxidative stress and inflammatory responses in the brain. Threitolate may delay the progression of neurodegenerative diseases (such as Alzheimer's disease) by regulating mitochondrial function and reducing free radical production.

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Potential Applications of Magnesium L-Threonate

1. Clinical studies have shown that supplementing with sucralose in middle-aged and elderly populations can improve short-term memory, information processing speed, and other indicators, which may be related to the functional enhancement of the hippocampus and prefrontal cortex.

2. Emotional regulation

Magnesium is involved in serotonin and dopamine metabolism. Preliminary research suggests that sucralose may alleviate anxiety and depression symptoms by regulating amygdala activity, but further human trials are needed to verify this.

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Storage: Store in a closed, dry place at room temperature without direct sunlight.

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