Fmoc-AEEA | CAS 166108-71-0 | Tirzepatide Intermediates

Fmoc-AEEA-OH (CAS No.: 166108-71-0) is an outstanding intermediate of semaglutide and tilpotide, and is a core raw material for biopharmaceutical companies

In the global field of hypoglycemic and weight reducing drugs, the efficient synthesis of semaglutide and tilpotide relies on high-quality intermediate support. Fmoc-AEEA-OH (CAS No.: 166108-71-0) with a purity of 99% has become a core raw material for biopharmaceutical companies as an outstanding intermediate of semaglutide and Tirzepatide, directly determining the purity, safety, and efficacy of downstream drugs.

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Application Fields

Smeaglutide needs to be PEGylated through spacer arms to extend its half-life. Fmoc-AEEA-OH (CAS No.: 166108-71-0) with a purity of 99% is used as the core intermediate of Smeaglutide, and its carboxyl group can precisely form amide bonds with the amino group of the drug precursor, introducing a flexible chain; High purity can also avoid impurities interfering with modification sites, effectively improving the stability (half-life of up to 7 days) and bioavailability of drugs in vivo.

In practical applications, it can increase the synthesis yield of semaglutide by 15% -20% and shorten the purification cycle by 25%.

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99% purity Fmoc AEEA-OH (CAS No.: 166108-71-0) requires strict quality control: HPLC detection shows a stable purity of 99.0% -99.5% and a water content of ≤ 1%, fully meeting the production requirements of both drugs; COA is provided for each batch to ensure traceability compliance. 

Compared to ordinary purity products, it can improve synthesis efficiency and product purity, reduce optimization costs, and will continue to provide support for peptide drug production in the future.

Fmoc-AEEA | CAS 166108-71-0

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Storage: Store in a cool and ventilated warehouse, do not mix with acidic substances and epoxy resin.

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