leuprorelin impurities

leuprorelin Impurities Synthesis | Omizzur
* For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Name

leuprorelin Impurities

TypePeptide impurities
Source

Solid phase peptide synthesis

Purity % (HPLC)> 95.0% 
Analysis HPLC,MS,COA
Pack size

Price ( USD )

Inventory
100 mgPlease inquireCustom made
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General Description

Leuprorelin Impurities Synthesis

leuprorelin acetate is a synthetic linear nine peptide, which is a powerful gonadotropin releasing hormone agonist. 

Impurities that may be produced in the process of leuproline acetate: process impurities brought in during the synthesis process, such as racemic impurities brought in by starting materials or produced in the reaction process (amino acids in this peptide chain are chiral, especially histidine his is a racemic amino acid), missing peptides produced because some amino acids are not connected (there may be incomplete reaction in the peptide chain after multi-step reaction), Peptide related substances such as broken peptides produced by peptide bond breaking and by-products formed by incomplete deprotection of amino acid side chains; There are a lot of amide bonds in the peptide chain, which is more unstable than general drugs, and it is easy to produce degradation products due to unstable factors such as deamidation, oxidation, hydrolysis, racemization and so on


Common leuproline impurities:

[4-D-serine]leuprorelin

[2-D-histidine]leuprorelin

[6-L-leucine]leuprorelin

[4-(O-acetyl-L-serine)]leuprorelin

[3-D-tryptophane]leuprorelin

[2-D-histidine,4-D-serine]leuprorelin

[5-D-tyrosine]leuprorelin

[7-D-leucine]leuprorelin

[1-(5-oxo-D-proline)]leuprorelin



Product Data Sheet

Name

Leuprorelin Impurities
TypePeptide impurities
Sourcecustom peptide synthesis
Analysis methodHPLC,MS,COA
Purity (HPLC)90%-95%
Salt typeTFA / None
Application It is mainly used to treat sex hormone related diseases, including advanced prostate cancer, endometriosis and central precocious puberty
ShippingFedex / by air
Delivery3-4 weeks


Shipping & Storage

It is valid for at least one year if stored at -20 ℃ or lower. Since each freezing and thawing of polypeptide will cause partial inactivation, after the storage solution with corresponding concentration is prepared for the first time (please prepare the storage solution according to the information in the column of reconstitution in the product introduction), it must be frozen at -20 ℃ or lower after sub packaging to avoid repeated freezing and thawing.

Shipping: By air or FedEx Express, delivery time: 5-10 days


Matters Needing Attention:

This product is freeze-dried powder. Since a small amount of polypeptide is deposited in the tube during the freeze-drying process, forming a very thin or invisible polypeptide layer, before opening the tube cover, we recommend centrifuging about 8000-12000g in a centrifuge for 10-30 seconds to make the polypeptide attached to the tube cover or tube wall gather at the bottom of the tube.

This product is only used for scientific research by professionals, and shall not be used for clinical diagnosis or treatment, food or drugs, or stored in ordinary houses.

For your safety and health, please wear lab clothes and disposable gloves.


Ordering Guide:

Quality Assurance

1. For all batches of products, we will keep samples after one year of validity. When customers raise objections, we can make a quick response.

2. For the products purchased by customers, an original of our inspection report will be attached with the goods, including batch number, date, etc.

3. If you have any problems in use, please feel free to contact us and we will help you solve them as soon as possible.


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2. Omizzur is a professional peptide manufacturer, there will be a huge discounts for bulk purchase. Distributors are welcomed. 


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