Peptide Knowledge Center
Peptide vaccines can be divided into three categories
1. Antiviral related peptide vaccines, including HBV, HIV, respiratory syncytial virus, etc;
2. Anti tumor related peptide vaccine, including tumor specific antigen polypeptide vaccine, oncogene and mutant tumor suppressor gene polypeptide vaccine;
3. Peptide vaccines against bacterial and parasitic infections, such as Mycobacterium tuberculosis short polypeptide vaccine, Schistosoma japonicum multi antigen polypeptide vaccine and CTL epitope polypeptide vaccine of falciparum malaria.
Peptide vaccine has more advantages than traditional vaccine
Polypeptide vaccine has the characteristics of safety, easy preparation, strong specificity, easy preservation and application. It overcomes many shortcomings of traditional vaccines, can be synthesized on a large scale, is easy to purify, and is very safe for human application. If some compounds are linked to short peptides to prepare internal adjuvants, the immune effect can be greatly improved. In addition, the preparation of multivalent vaccine can prevent a variety of diseases at the same time. Especially it is widely used in tumor treatment, which can reduce the huge side effects brought by radiotherapy and chemotherapy, and has specific killing effect on tumor cells. These characteristics indicate that peptide vaccine may be the development direction of vaccinology.
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