Peptide Knowledge Center

Sulfur-Containing Amino Acid Derivative 1: N-Acetyl-L-Cysteine

Sulfur-containing amino acid derivatives are mainly derived from three common sulfur-containing amino acids-methionine, cysteine, and cystine. At the same time, it also has the functions of anti-oxidation, scavenging free radicals, etc., and has important application value in medicine and food. There are many sulfur-containing amino acid derivatives, among which the most representative ones are N-acetyl-L-cysteine, glutathione, and adenosylmethionine.


Methionine, cysteine and cystine are common sulfur-containing amino acids, "with important nutritional and physiological regulatory functions. Many derivatives can be formed from these three amino acids, the most representative of which are N-acetyl-L-cysteine, glutathione and adenosylmethionine. The common feature of these compounds is that they contain sulfur, the so-called sulfhydryl group. It is precisely because of this active group that this type of compound has important physiological functions. Sulfur-containing amino acid derivatives are an important focus of current research and development.


Cysteine and its derivatives are widely used in medicine, such as antitussive, expectorant, anti-inflammatory, antipyretic, analgesic, inhibiting the growth of bacteria and tumors, increasing white blood cells, etc. Therefore, L-cysteine derivatives have attracted great attention from the medical community at home and abroad.


N-Acetyl-L-cysteine "is a mucolytic agent in the respiratory tract", which can decompose white viscous phlegm and thick phlegm, "improve the patient's breathing condition; it can also be made into eye drops" for the treatment of various keratitis; can also be used to treat, prevent or alleviate hair loss due to oxidative damage or during chemotherapy. In vivo, it participates in various important metabolisms, can promote the synthesis of glutathione, and is of great significance for maintaining the reduced state of cells. In addition, it can be used as an inhibitor to inhibit tissue and cell necrosis caused by carcinogenesis, and it can be used to treat external damage and central nervous system, visual tissue damage and Parkinson's disease caused by lipid peroxidation caused by nervous system disorders. It is widely used in medicine.


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