2-chlorotrityl chloride resin

2-Chlorotrityl Chloride Resin | Omizzur Peptide
* For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

2 Chlorotrityl Chloride Resin



Molecular FormulaC19H14Cl2
Pack size

CIF Price ( USD )

25g$  70.0
In stock
100gPlease inquire the lowest
In stock
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General Description

2 Chlorotrityl Chloride Resin | Omizzur Peptide

Biotechnological Applications

The 2-chlorotrityl chloride (2-CTC) resin is one of the most frequently used and most versatile resins for the large-scale manufacture of peptides. It is slightly less acid-labile than Trityl Resin and thus more widely used in solid phase peptide synthesis. Peptides UBI-8 and UBI-9 were synthesized by Fmoc-solid phase chemistry using a 2-chlorotrityl chloride linker-resin. 

Trityl linkers have certain advantages in comparison to the alkoxybenzyl alcohol (eg. Wang resin), especially in the area of peptide chemistry. First, the problem of racemization during the loading of the first amino acid (using DIPEA) is avoided with trityl linkers. Second, due to steric factors, no diketopiperazine formation is observed.

2 Chlorotrityl Chloride resins is used in convergent peptide synthesis. Extremely acid labile resin for preparing peptide acids and partially protected peptide fragments by the Fmoc strategy. Cleavage can be effected by using AcOH/TFE/DCM or 0.5% TFA.

2-Chlorotrityl chloride is also used as an intermediate of clotrimazole. It is also used in the preparation of modified trityl nucleosides as inhibitors of P. falciparum dUTPase. In addition, it serves as a protecting group reagent for carboxylic acids forming esters.

2 Chlorotrityl Chloride Resin Synthesis:

2-chlorotrityl chloride resin

Product Data Sheet

2 Chlorotrityl Chloride Resin COA


2 Chlorotrityl Chloride Resin





Molecular Formula


Molecular Weight


Melting point

130-135 C

Boiling point

421.3±40.0 °C(Predicted)

100-200 mesh

1% DVB

Storage temp.


Shipping & Storage

Shipping: Deliver to worldwide by Fedex / DHL / By air

Information attached with the products: HPLC/MS/COA analysis report

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