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Vasopressin (AVP), also known as vasopressin and antidiuretic hormone, is a cyclic peptide hormone produced by neurons in the supraoptic nucleus of the hypothalamus. Vasopressin is mainly used for the treatment of diabetes insipidus, esophageal varices bleeding, and also for the differential diagnosis of central diabetes insipidus, nephrogenic diabetes insipidus and mental polydipsia.
Vasopressin exists as a free peptide in the blood circulation. AVP was successfully synthesized in 1954. AVP plays an important role in regulating the reabsorption of free water, the isotonic concentration of body fluids, blood volume, blood pressure, cell contraction, cell proliferation and the secretion of adrenocorticotropic hormone (ACTH). AVP is synthesized and stored in the hypothalamus, and after reaching a certain concentration, it is transported down the nerve bundle, through the conus arteriosus to the nerve endings of the posterior pituitary, where it is released into the systemic circulation.
In the process of studying vasopressin analogs, due to the structural similarity between the compounds and vasopressin or oxytocin, the pharmacopoeia of various countries have successively issued guidelines for impurity control, and adopted "known impurities" and "single unknown impurities". , oxytocin and "total impurities" to achieve control of impurities in chemicals. Common vasopressin analogs are: desmopressin acetate, oxytocin, benlypressin, lysinepressin, Terlipressin, Carbetocin, etc. Omizzur supplies all types of vasopressin and analogs, as well as all vasopressin-related impurities.
Product Data Sheet
HPLC & COA & MS
Shipping & Storage
It is valid for at least one year if stored at -20 ℃ or lower. Since each freezing and thawing of polypeptide will cause partial inactivation, after the storage solution with corresponding concentration is prepared for the first time (please prepare the storage solution according to the information in the column of reconstitution in the product introduction), it must be frozen at -20 ℃ or lower after sub packaging to avoid repeated freezing and thawing.
Shipping: By air or FedEx Express, delivery time: 5-10 days
Matters Needing Attention:
This product is freeze-dried powder. Since a small amount of polypeptide is deposited in the tube during the freeze-drying process, forming a very thin or invisible polypeptide layer, before opening the tube cover, we recommend centrifuging about 8000-12000g in a centrifuge for 10-30 seconds to make the polypeptide attached to the tube cover or tube wall gather at the bottom of the tube.
This product is only used for scientific research by professionals, and shall not be used for clinical diagnosis or treatment, food or drugs, or stored in ordinary houses.
For your safety and health, please wear lab clothes and disposable gloves.
1. For all batches of products, we will keep samples after one year of validity. When customers raise objections, we can make a quick response.
2. For the products purchased by customers, an original of our inspection report will be attached with the goods, including batch number, date, etc.
3. If you have any problems in use, please feel free to contact us and we will help you solve them as soon as possible.
1. After you confirm the purchase, please inform our sales staff of your detailed requirements, including product name, quantity, packaging requirements, etc., as well as your receiving address, company name and contact information; Then our sales staff will make an order for you.
2. Omizzur is a professional peptide manufacturer, there will be a huge discounts for bulk purchase. Distributors are welcomed.
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