Leuprorelin CAS 53714-56-0
* For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.


Type GnRHa


Purity % (HPLC)> 99.0% (HPLC)
Pack size

Price ( USD )

100mg$  /
In stock
1 gPlease inquire
In stock
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General Description

Leuprorelin / Leuprolide  CAS 53714-56-0

Endometriosis is an estrogen dependent disease, which mostly occurs in women of childbearing age. The menstrual cycle of patients is short. Ectopic endometrial implants will lead to inflammation, scar and adhesion, and produce symptoms such as chronic pelvic pain, fatigue, dysmenorrhea, difficult sexual intercourse, periodic bleeding, difficult urination or defecation. In severe cases, it will lead to infertility. Surgery is the first choice for clinical treatment of endometriosis, but the recurrence rate is high. Therefore, in order to improve the treatment effect and reduce the recurrence rate, drug treatment is often given after operation. The initial treatment drugs include non steroidal anti-inflammatory drugs, compound oral contraceptives, etc., and then androgens, progesterone, gonadotropin releasing hormone analogue (GnRHa) and other main stream treatment drugs are gradually developed.

Leuproline is a highly active analogue of luteinizing hormone releasing hormone (GnRH) produced in the hypothalamus. It is a synthetic water-soluble nine peptide with two ends closed. Leuproline mainly regulates endocrine to treat prostate cancer, breast cancer, endometriosis and other sex hormone related diseases. Leuproline was ineffective after oral administration, and was well absorbed by subcutaneous or intramuscular injection. At present, its sustained-release preparations are mostly used in clinic.

Application of leuprorelin

  • Endometriosis

  • Adjuvant therapy for breast cancer

  • Fibroid

  • Adenomyosis of uterus

  • Central precocious puberty

  • Prostatic cancer

  • Assisted ovulation and in vitro fertilization

Product Data Sheet


Leuprorelin / leuprolide

CAS53714-56-0 (net), 74381-53-6 (acetate)
TypeGonadotropin releasing hormone analogue
Molecular formulaC59H84N16O12
Molecular Weight1209.4
Purity (HPLC)99.0%
Sourcecustom peptide synthesis
Storage-20 ± 5°C

Shipping & Storage

It is valid for at least one year if stored at -20 ℃ or lower. Since each freezing and thawing of polypeptide will cause partial inactivation, after the storage solution with corresponding concentration is prepared for the first time (please prepare the storage solution according to the information in the column of reconstitution in the product introduction), it must be frozen at -20 ℃ or lower after sub packaging to avoid repeated freezing and thawing.

Shipping: By air or FedEx Express, delivery time: 5-10 days

Matters Needing Attention:

This product is freeze-dried powder. Since a small amount of polypeptide is deposited in the tube during the freeze-drying process, forming a very thin or invisible polypeptide layer, before opening the tube cover, we recommend centrifuging about 8000-12000g in a centrifuge for 10-30 seconds to make the polypeptide attached to the tube cover or tube wall gather at the bottom of the tube.

This product is only used for scientific research by professionals, and shall not be used for clinical diagnosis or treatment, food or drugs, or stored in ordinary houses.

For your safety and health, please wear lab clothes and disposable gloves.

Ordering Guide:

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