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The anticancer drug cetrorelix is a newly synthesized gonadotropin releasing hormone antagonist, which controls the secretion of luteinizing hormone (LH) and follicle stimulating hormone (FSH) by competing with endogenous LHRH for membrane receptors on pituitary cells. A large number of studies have shown that cetrorelix has a good effect on ovarian cancer, prostate cancer, uterine fibroma, endometriosis and other diseases, and can prevent and improve benign prostatic hypertrophy and ovarian hyperstimulation syndrome.
As a newly synthesized gonadotropin releasing hormone antagonist, cetrorelix can treat, prevent and alleviate various diseases through three ways:
1. hypothalamic pituitary gonadal pathway inhibits the secretion of dependent hormones
2. directly inhibit the proliferation and metastasis of tumor cells
3. inducing apoptosis of cancer cells.
A large number of studies have shown that cetrorelix has a good effect on ovarian cancer, prostate cancer, uterine fibroma, endometriosis and other diseases, and can prevent and improve benign prostatic hypertrophy and ovarian hyperstimulation syndrome. With the in-depth study of the mechanism of inhibiting cancer cells and a large number of clinical trials, cetrorelix will become a widely used cancer drug.
Omizzur synthesized cetrorelix by solid-phase peptide synthesis method. The two fragments were synthesized at the same time, which shortened the product synthesis cycle. The yield of cetrorelix crude product was as high as 90%. Less by-products, convenient for industrial production. At the same time, Omizzur supply all kinds of cetrorelix impurities.
Product Data Sheet
|Description||Cetrorelix Acetate is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH)|
|Reconstitution||Dissolve in distilled water or DMSO|
Shipping & Storage
It is valid for at least one year if stored at -20 ℃ or lower. Since each freezing and thawing of polypeptide will cause partial inactivation, after the storage solution with corresponding concentration is prepared for the first time (please prepare the storage solution according to the information in the column of reconstitution in the product introduction), it must be frozen at -20 ℃ or lower after sub packaging to avoid repeated freezing and thawing.
Shipping: By air or FedEx Express, delivery time: 5-10 days
Matters needing attention:
This product is freeze-dried powder. Since a small amount of polypeptide is deposited in the tube during the freeze-drying process, forming a very thin or invisible polypeptide layer, before opening the tube cover, we recommend centrifuging about 8000-12000g in a centrifuge for 10-30 seconds to make the polypeptide attached to the tube cover or tube wall gather at the bottom of the tube.
This product is only used for scientific research by professionals, and shall not be used for clinical diagnosis or treatment, food or drugs, or stored in ordinary houses.
For your safety and health, please wear lab clothes and disposable gloves.
1. For all batches of products, we will keep samples after one year of validity. When customers raise objections, we can make a quick response.
2. For the products purchased by customers, an original of our inspection report will be attached with the goods, including batch number, date, etc.
3. If you have any problems in use, please feel free to contact us and we will help you solve them as soon as possible.
1. After you confirm the purchase, please inform our sales staff of your detailed requirements, including product name, quantity, packaging requirements, etc., as well as your receiving address, company name and contact information; Then our sales staff will make an order for you.
2. Omizzur is a professional peptide manufacturer, there will be a huge discounts for bulk purchase. Distributors are welcomed.
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