Angiotensin acetate CAS 58-49-1

Hypertension is not only a common disease, but also a non-negligible risk factor leading to various cardiovascular events. According to research, the main pathological factor leading to the increase in the incidence of cardiovascular events is the changes in the structure and function of target organs, and the renin-angiotensin system cannot be ignored. system, RAS), especially angiotensin.

Angiotensin is a kind of peptide substance with strong vasoconstriction and stimulation of adrenal cortex to secrete aldosterone, which is involved in the regulation of blood pressure and body fluids. It can be divided into angiotensin I-VII, and there are many studies in angiotensin I, angiotensin II, and angiotensin III.

AngiotensinI~III

Angiotensin I can stimulate the adrenal medulla to secrete epinephrine, and its direct effect on vasoconstriction is not obvious;

Angiotensin Ⅱ can constrict the arterioles of the whole body and increase blood pressure. In addition, it can also promote the secretion of aldosterone by the adrenal cortex, and aldosterone acts on the renal tubules to retain sodium, water, and potassium, resulting in increased blood volume;

The vasoconstriction effect of angiotensin III is weak, only 1/5 of that of angiotensin II, but the effect of promoting the secretion of aldosterone is stronger than that of angiotensin II. Omizzur provides high-purity angiotensin by solid-phase peptide synthesis.

It is valid for at least one year if stored at -20 ℃ or lower. Since each freezing and thawing of polypeptide will cause partial inactivation, after the storage solution with corresponding concentration is prepared for the first time (please prepare the storage solution according to the information in the column of reconstitution in the product introduction), it must be frozen at -20 ℃ or lower after sub packaging to avoid repeated freezing and thawing.

Shipping: By air or FedEx Express, delivery time: 5-10 days

Matters Needing Attention:

This product is freeze-dried powder. Since a small amount of polypeptide is deposited in the tube during the freeze-drying process, forming a very thin or invisible polypeptide layer, before opening the tube cover, we recommend centrifuging about 8000-12000g in a centrifuge for 10-30 seconds to make the polypeptide attached to the tube cover or tube wall gather at the bottom of the tube.

This product is only used for scientific research by professionals, and shall not be used for clinical diagnosis or treatment, food or drugs, or stored in ordinary houses.

For your safety and health, please wear lab clothes and disposable gloves.

Quality Assurance

1. For all batches of products, we will keep samples after one year of validity. When customers raise objections, we can make a quick response.

2. For the products purchased by customers, an original of our inspection report will be attached with the goods, including batch number, date, etc.

3. If you have any problems in use, please feel free to contact us and we will help you solve them as soon as possible.

Order Guidance

1. After you confirm the purchase, please inform our sales staff of your detailed requirements, including product name, quantity, packaging requirements, etc., as well as your receiving address, company name and contact information; Then our sales staff will make an order for you.  

2. Omizzur is a professional peptide manufacturer, there will be a huge discounts for bulk purchase. Distributors are welcomed.